Principal investigator: Zhi-Hong Mao

University: University of Pittsburgh

Industry partner(s): AiMiLight Sensors and Intelligent Systems Inc.

This Pennsylvania manufacturing innovation project aims to develop transformative technology for producing micro-optical fluidic chips with broad applications in medical devices and chemical engineering. Leveraging cutting-edge laser additive manufacturing, the project will create a new class of microfluidic devices capable of utilizing biocompatible polymer materials for fabrication. These advancements will enable superior drug absorption performance, surpassing current industry leaders.

Through an innovative additive manufacturing process, the project will also develop microfluidic chips with embedded on-chip sensors for bioassays and chemical analysis, significantly enhancing the functionality of these devices. In collaboration with a translational medical research partner, the project will validate device functionality by demonstrating its application in on-chip immunotherapy for cancer treatment.

The success of this initiative will establish a strong foundation for developing and commercializing advanced microfluidic technology in Western Pennsylvania, fostering innovation and growth in the region.