Principal investigators: Longyan Chen and Xiaoxu Ji

University: Gannon University

Industry partner: Glacier Scalp Cooling, LLC

Each year, approximately 650,000 cancer patients receive chemotherapy in the United States, with 65% experiencing Chemotherapy-Induced Alopecia (CIA). The psychological impact is profound—47% of women cite hair loss as the most traumatic part of treatment, and 8% consider declining life-saving chemotherapy due to the fear of hair loss. While scalp cooling technology has shown significant promise in preventing CIA, current solutions are limited by clinical constraints and lack personalization.

Gannon University, in partnership with Glacier Scalp Cooling LLC, proposes to develop a novel portable and wearable scalp cooling system for continuous use from infusion center to home. The proposed device will integrate miniaturized cooling components into a lightweight, portable design with precise temperature regulation. Supported by the Manufacturing PA Innovation Program, this project will establish advanced medical device manufacturing in Erie, PA, creating regional high-tech jobs while offering a scalable, viable product that improves patients’ life quality.